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. 2022 Dec 13;17(12):e0278998. doi: 10.1371/journal.pone.0278998

Table 4. Interaction of current cigarette smoking and NAT2 acetylator phenotype on diminished ovarian reserve (DOR).

All womena Women without PCOSb
Rapid/Intermediate Slow Rapid/Intermediate Slow
N OR (95% CI) N OR (95% CI) N OR (95% CI) N OR (95% CI)
Nonsmoker 38 1.00 25 0.42(0.05–3.44) 26 1.00 16 0.35(0.02–5.14)
Passive smoker 39 1.16(0.30–4.50) 24 2.42(0.37–15.97) 25 1.43(0.31–6.66) 9 1.92(0.11–33.78)
Active smoker 18 1.25(0.16–9.54) 11 1.59(0.26–9.70) 13 1.71(0.17–17.12) 3 2.50(0.15–42.6)

a Adjusted for age, race, and polycystic ovary syndrome; p-value for interaction = 0.67

b Adjusted for age and race; p-value for interaction = 0.69