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. 2022 Nov 28;2023(1):hoac053. doi: 10.1093/hropen/hoac053

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© The Author(s) 2022. Published by Oxford University Press on behalf of European Society of Human Reproduction and Embryology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 6. — Achievement of pregnancy 14 days following unilateral treatment to the uterine horns of mice with ethanol-damaged endometrium. Fertility restoration was assessed by (A) pregnancy rate (number of embryos per horn by total number of embryos), (B) number of embryos per horn, (C) embryo weight and (D) representative images of gestational uterine horns and embryo morphology, 14 days after confirmed mating by vaginal plug (stage E14.5 of embryo development). Right uterine horns were treated with saline, hUC-PRP or EndoECM + hUC-PRP, while contralateral left horns only underwent sham surgery. (A–C) Data are presented as mean ± SD, n = 10 per group. A statistical significance of P < 0.05 is indicated by the asterisk. hUC-PRP, platelet-rich plasma from human umbilical cord; EndoECM, decellularized porcine endometrium-derived extracellular-matrix hydrogel.