TABLE 3.
HCTZ versus CTD one‐on‐one comparison
| EA patients (%) | AA patients (%) | |
|---|---|---|
| N = 35 | N = 15 | |
| Comparison based on SBP response | ||
| Clinically meaningful benefit with HCTZ over CTD (≥3 mmHg) | 5 (14) | 3 (20) |
| Similar response with both drugs | 6 (17) | 2 (13) |
| Clinically meaningful benefit with CTD over HCTZ (≥3 mmHg) | 24 (69) | 10 (67) |
| Comparison based on DBP response | ||
| Clinically meaningful benefit with HCTZ over CTD (≥3 mmHg) | 3 (9) | 3 (20) |
| Similar response with both drugs | 14 (40) | 8 (53.3) |
| Clinically meaningful benefit with CTD over HCTZ (≥3 mmHg) | 18 (51) | 4 (27) |
Note: Values are n (%). Similar response = magnitude of difference between BP change on HCTZ and BP change on CTD is <3 mmHg.
Abbreviations: AA, African American; BP, blood pressure; CTD, chlorthalidone; DBP, diastolic blood pressure; EA, European American; HCTZ, hydrochlorothiazide; SBP, systolic blood pressure.