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. 2022 Nov 23;62(1):11. doi: 10.3892/ijo.2022.5459

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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RNA-sequencing analysis confirms the effect of TFP on cell cycle. (A) Top 20 results of the GO pathway enrichment based on the DEGs identified in TFP-treated B16 allograft. In the scatter plot, the RichFactor corresponds to the ratio of the number of DEGs noted in a pathway term to all the genes noted in such pathway term, and a greater RichFactor means greater intensity. The Q-value is the corrected P-value ranging from 0 to 1, and a lower Q-value represents greater intensity. (B) GSEA revealed that cell cycle-related genes were significantly regulated. TFP, Tremella fuciformis-derived polysaccharide; GO, Gene Ontology; DEGs, differentially expressed genes; GSEA, Gene set enrichment analysis.