Table 2.
Patient demographic and clinical characteristics by vaccination status and dose.
| Characteristica | Vaccination Status (n = 777, UNK=123) |
Breakthrough infection after vaccine dose (n = 529, UNK=55) |
|||||
|---|---|---|---|---|---|---|---|
| Unvaccinated (n = 193,24.8 %) | Vaccinated (n = 584,75.2 %) | (P-value) | First dose (n = 241,45.6 %) | Second dose (n = 267, 50.5 %) | Booster (n = 21,3.9 %) | (P-value) | |
| Age (mean, SD) years | 33.4(20.3) | 37.3(11.5) | (0.0011)b | 37.6(9.9) | 36.9(12.3) | 38.6(9.6) | (0.022)b |
| Ct (mean, SD) | 23.9(6.2) | 23.6(5.5) | (0.57) | 23.6(5.6) | 23.4(5.4) | 25(4.3) | (0.45) |
| Gender (n = 773) | |||||||
| Male (n = 354) | 84(10.9) | 270(34.9) | (0.56) | 133(25.6) | 99(19.0) | 12(2.3) | (0.0002)b |
| Female (n = 419) | 107(13.8) | 312(40.4) | 106(20.4) | 162(31.2) | 8(1.5) | ||
| Age Group (n = 774) years | |||||||
| (0–19) (n = 67) | 46(5.9) | 21(2.7) | (0.0001)b | 2(0.4) | 11(2.11) | 0 | (0.13) |
| (20–29) (n = 186) | 39(5.0) | 147(19.0) | 57(10.9) | 70(13.4) | 3(0.6) | ||
| (30–39) (n = 233) | 35(4.5) | 198(25.6) | 89(17.1) | 90(17.2) | 8(1.5) | ||
| (40–49) (n = 160) | 25(3.2) | 135(17.4) | 62(11.9) | 53(10.2) | 8(1.5) | ||
| (50–59) (n = 87) | 27(3.5) | 60(7.8) | 27(5.2) | 26(3.9) | 2(0.4) | ||
| (60–102) (n = 41) | 18(2.3) | 23(3.0) | 3(0.60) | 12(2.3) | 1(0.2) | ||
| Nationality (n = 715) | |||||||
| Saudi (n = 438) | 147(20.6) | 291(38.7) | (0.0001)b | 142(28.9) | 100(20.3) | 11(2.2) | (0.0001)b |
| Non-Saudi (n = 277) | 17(2.4) | 260(36.4) | 90(18.3) | 142(28.9) | 7(1.4) | ||
| Symptoms Observed (n = 777) | |||||||
| Asymptomatic (n = 45) | 10(1.3) | 35(4.5) | (0.67) | 10(1.9) | 16(3.1) | 3(0.60) | (0.11) |
| Symptomatic (n = 732) | 183(23.6) | 549(70.7) | 230(44.1) | 246(47.1) | 17(3.3) | ||
| ICU Admission (n = 672) | |||||||
| No (n = 659) | 167(24.9) | 492(73.2) | (0.0032)b | 158(36.0) | 258(58.8) | 20(4.5) | (0.54) |
| Yes (n = 13) | 8(1.2) | 5(0.7) | 2(0.46) | 1(0.2) | 0 | ||
| Comorbidity (n = 777) | |||||||
| No (n = 488) | 84(10.8) | 404(52.0) | (0.0001)b | 221(42.3) | 144(27.6) | 14(2.7) | (0.0001)b |
| Yes (n = 289) | 109(14.0) | 180(23.2) | 19(3.6) | 118(22.6) | 6(1.2) | ||
| Hypertension (n = 777) | |||||||
| No (n = 707) | 175(22.5) | 532(68.5) | (0.85) | 234(44.8) | 229(43.8) | 19(3.6) | (0.0001)b |
| Yes (n = 70) | 18(2.3) | 52(6.7) | 6(1.2) | 33(6.3) | 1(0.2) | ||
| Diabetes Mellitus (n = 777) | |||||||
| No (n = 712) | 175(22.5) | 537(69.1) | (0.57) | 235(45) | 232(44.4) | 19(3.6) | (0.0001)b |
| Yes (n = 65) | 18(2.3) | 47(6.1) | 5(1.0) | 30(5.6) | 1(0.2) | ||
| Ct Value Range (n = 607) | |||||||
| High (Ct > 30) (n = 86) | 23(3.8) | 63(10.4) | (0.73) | 28(7.0) | 23(5.7) | 3(0.8) | (0.0002)b |
| Low (20 <;Ct) (n = 144) | 33(5.4) | 111(18.3) | 46(11.4) | 51(12.7) | 4(1.0) | ||
| Moderate (20–30) (n = 377) | 98(16.1) | 279(46.0) | 64(15.9) | 172(42.8) | 11(2.7) | ||
Ct indicates cycle threshold; ICU, intensive care unit; UNK, unknown.
a
Not all characteristics sum to 900 patients owing to missing data.
b
P values< 0.05 considered statistically significant.