TABLE 2.
Pediatric Acute Lung Injury and Sepsis Investigators Consensus Conference Topics, Publications and Potential Impact
| Years | Consensus Conference | Topics Covered | Journal |
|---|---|---|---|
| 2005 | International Sepsis Forum on Sepsis in Infants and Children | Definitions of sepsis, organ dysfunction, and specific infections in critically ill children focusing on specific populations and implications for future studies | Pediatr Crit Care Med May 2005; Supplement 3 |
| 2012–2014 (updating 2020–2022) | Pediatric Acute Lung Injury Consensus Conference | Definition of pediatric acute respiratory distress syndrome and Grading of Recommendations, Assessment, Development, and Evaluation method recommendations for its management | Pediatr Crit Care Med June 2015; 16:428–439 and Supplement |
| 2014–2017 | Transfusion and Anemia Expertise Initiative | Decision-making for RBC transfusion management and research priorities for transfusion in critically ill children including in nine specific populations | Pediatr Crit Care Med Sept 2018; 19:884–898 and Supplement |
| 2016–2017, and 2019 | Hepatic veno-occlusive disease after haemopoietic stem-cell transplantation | Diagnosis, grading, and treatment recommendations for children, adolescents, and young adults with sinusoidal obstructive syndrome | Biol Blood Marrow Transplant Nov/Dec 2017 and Feb 2018 |
| Lancet Haematol 2020; 7:e61–e72 | |||
| 2018 | CAR-T-cell therapy in pediatric oncology patients | Management guidelines for pediatric patients receiving CAR-T therapy | Nat Rev Clin Oncol 2019; 16:45–63 |
| 2017–2021 | Pediatric Organ Dysfunction Information Update Mandate | Single-organ dysfunction definitions for neurologic, cardiovascular, respiratory, gastrointestinal, acute liver, renal, hematologic, coagulation, endocrine, endothelial, and immune system dysfunction | Pediatrics 2022 January Supplement |
| 2018–2020 | PICU Research COS | Development of a core outcomes set for research and clinical programs for children in the PICU | Crit Care Med 2020; 48:1819–1828 |
| 2019–2022 | Pediatric ECMO Anticoagulation Collaborative | Develop consensus statements for management of pediatric patients receiving ECMO support | Ongoing, funded by National Institutes of Health R13HD104432 |
| 2019–2022 | Ventilator Liberation | Practice guidelines for liberating children from mechanical ventilator support | Am J Respir Crit Care Med 2022; Aug |
| 2020–2022 | Core Outcomes Measurement Set (PICU Core Outcomes Measurement Set | The core outcomes measurement set is to measure specific outcomes in the PICU COS | Pediatr Crit Care Med Aug 2022; 19:884–898 and Supplement |
| 2020–2022 | Transfusion and Anemia EXpertise Initiative-Control/Avoidance of Bleeding | Plasma and platelet transfusion strategies in critically Ill children following severe trauma, traumatic brain injury, and/or intracranial hemorrhage | Pediatr Crit Care Med Sept 2018; 19:884–898, Jan 2022; 23:34–51, and Supplement |
CAR-T = chimeric antigen receptor T cell, COS = core outcome set, ECMO = extracorporeal membrane oxygenation, TAXI = Transfusion Anemia Expertise Initiative.