Table 3.
Secondary outcomes
| Outcome | No DD N = 112 |
Persistent DD N = 10 |
P value | |
|---|---|---|---|---|
| Relative risk (95% CI) | ||||
| NIV or HFO > 48 hr (days), n/total N (%) | 3/112 (3%) | 4/10 (40%) | 15 (4 to 52) | < 0.001a |
| Mechanical ventilation > 24 hr, n/total N (%) | 1/112 (1%) | 4/10 (40%) | 45 (7 to 278) | < 0.001a |
| Pneumonia, n/total N (%) | 7/112 (6%) | 4/10 (40%) | 6 (2 to 16) | 0.006a |
| Reintubation, n/total N (%) | 1/112 (1%) | 4/10 (40%) | 45 (7 to 278) | < 0.001a |
| Atelectasis requiring bronchoscopy, n/total N (%) | 2/112 (2%) | 3/10 (30%) | 17 (4 to 75) | 0.004a |
| Mortality, n/total N (%) | 0/112 (0%) | 1/10 (10%) | - | 0.08a |
| Difference in medians (95% CI) | ||||
|---|---|---|---|---|
| Duration of NIV or HFO (hr), median [IQR] | 0 [0–0] | 8 [0–34] | 8 (0 to 22) | < 0.00b |
| Duration of mechanical ventilation (hr), median [IQR] | 3 [2–4] | 5 [3–257] | 2 (1 to 41) | 0.008b |
| Postoperative Us-troponin peak, median [IQR] | 2.4 [1.2–4.3] | 2.4 [1.3–5.0] | 0.1 (-1.3 to 1.9) | 0.82b |
| Postoperative creatine kinase, median [IQR] peak | 495 [340–809] | 666 [357–1,114] | 171 (-151 to 477) | 0.38b |
| Length of stay in ICU (days), median [IQR] | 4 [2–6] | 8 [5–29] | 4 (2 to 12) | 0.002b |
| Length of stay in hospital (days), median [IQR] | 10 [8–12] | 11 [8–29] | 0.5 (-1 to 12) | 0.24b |
aFisher’s exact test
bMann–Whitney test
CI = confidence interval; DD = diaphragm dysfunction; HFO = high-flow oxygen; ICU = intensive care unit; IQR = interquartile range; NIV = noninvasive ventilation