Table 3. Interobserver Agreement and Agreement between the Automated and Manually Measured Native T1 and ECV Fraction.
| Comparison | ICC (95% Confidence Interval)* | |
|---|---|---|
| Native T1 | ECV | |
| Reader 1–reader 2 | 0.98 (0.78–1.00) | 0.99 (0.86–1.00) |
| Reader 1–reader 3 | 0.97 (0.59–0.99) | 0.99 (0.88–1.00) |
| Reader 1–reader 4 | 1.00 (0.97–1.00) | 1.00 (1.00–1.00) |
| Reader 2–reader 3 | 1.00 (0.97–1.00) | 1.00 (1.00–1.00) |
| Reader 2–reader 4 | 1.00 (1.00–1.00) | 1.00 (0.99–1.00) |
| Reader 3–reader 4 | 0.99 (0.97–1.00) | 1.00 (0.99–1.00) |
| Among four readers | 0.99 (0.96–0.99) | 0.99 (0.99–1.00) |
| Automatic–reader 1 | 0.98 (0.95–0.99) | 0.99 (0.98–0.99) |
| Automatic–reader 2 | 0.99 (0.98–0.99) | 0.98 (0.97–0.99) |
| Automatic–reader 3 | 0.98 (0.95–0.99) | 0.99 (0.97–0.99) |
| Automatic–reader 4 | 0.99 (0.98–0.99) | 0.99 (0.98–0.99) |
| Automatic–average of four readers | 0.99 (0.99–0.99) | 0.99 (0.98–0.99) |
*Based on per-subject basis. ECV = extracellular volume, ICC = intraclass correlation coefficient