FIG. 3.

ELISA ODs for fecal C. parvum antigen in SCID mice in the weeks following transfer of 10⁷ spleen cells from DO11.10 RAG^−/− donors (□ [n = 8]), DO11.10 RAG^−/− donors followed by 0.5-mg ovalbumin injections (▵ [n = 5]), C10.4 Tg donors (⧫ [n = 5]), CD154^−/− DO11.10 donors (◊ [n = 4]), or C57BL/6 wild-type donors (▴ [n = 6]). ■, six controls injected with ovalbumin but no cells; ●, OD for six uninfected controls; ○, positive control supplied by the kit manufacturer. The ODs at ≥10 weeks for the animals receiving DO11.10 RAG^−/− cells without ovalbumin and the wild-type controls differ (P < 0.05) from those for the other four C. parvum-infected groups. Data points represent the mean + 1 standard deviation.