TABLE 2.

Percentage of CD4⁺ cells in spleens of C. parvum-infected SCID mice injected with DO11.10 cells^a

Group	Treatment	% of CD4+ cells in spleen
1	Ovalbumin injected alone	<1
2	107 DO11.10 cells	35 ± 7
3	107 DO11.10 cells + ovalbumin	21 ± 6
4	107 BALB/c cells	38 ± 5

^aGroups of six BALB/c SCID mice were infected with C. parvum. Four weeks later, groups 2 to 4 were given 10⁷ DO11.10 or control spleen cells by i.p. injection. The percentage of CD4⁺ cells in spleen ± 1 standard deviation was determined after necropsy by FACS analysis, 12 weeks after cell transfer. Groups 2 and 4 do not differ significantly, while group 3 is significantly lower than group 2 or 4 (P < 0.04).