Table 2.
Unadjusted relationships between serum ferritin groups and clinical outcomes.
| Low-ferritin group | NRR group | High-ferritin group | p 1, p2 value | |
|---|---|---|---|---|
| Hospital mortality (%) | 2 (9.52) | 87 (11.73) | 416 (24.64) | 1.000, <0.001 |
| ICU mortality (%) | 2 (9.52) | 60 (8.09) | 304 (18.01) | 1.000, <0.001 |
| 28-day mortality (%) | 1 (4.76) | 114 (15.36) | 431 (25.53) | 0.543, <0.001 |
| 90-day mortality (%) | 4 (19.05) | 167 (22.51) | 602 (35.66) | 1.000, <0.001 |
| Hospital LOS (days) | 5.2 (3.7, 7.9) | 9.8 (5.8, 17.5) | 14.3 (7.5, 24.4) | 0.012, <0.001 |
| ICU-LOS (days) | 1.8 (1.1, 2.3) | 3.7 (2.0, 8.5) | 6.0 (2.8, 13.4) | 0.008, <0.001 |
| AKI (%) | 9 (42.86) | 526 (70.89) | 1,364 (80.81) | 0.018, <0.001 |
| Vasopressor use (%) | 3 (14.29) | 252 (33.96) | 670 (39.69) | 0.177, 0.021 |
| SOFA score | 3 (2, 4) | 3 (2, 4) | 4 (2, 5) | 1.000, <0.001 |
p1 value represents the p value of comparisons between the low-ferritin group and the NRR group, while p2 value represents the p value of comparisons between the NRR group and the high-ferritin group. NRR: normal reference range; ICU: intensive care unit; LOS: length of stay; AKI: acute kidney injury; SOFA score: the sequential organ failure assessment.