Table 2.

Inflammatory biomarker levels of 31 African American women with parental history of AD.

	Total	Normal IL-10 (n = 17)	Elevated IL-10 (n = 14)	Mean Difference	Raw p	Effect Sizes Cohen’s d (95% Cl) (Raw)	Multivariate Adj M Difference	p (Adj)
TGFα ^	1.22 ± 1.46	0.62 ± 0.74	1.95 ± 1.78	−1.32 (0.25,2.4)	0.019	−1.01 (−1.8, −0.2)	−1.18 (−2.4, 0.1)	0.062
IFNg ^	11.72 ± 6.97	8.65 ± 4.46	15.45 ± 7.77	−6.8 (1.91,11.69)	0.009	−1.1 (−1.9, −0.3)	−6.86 (−12.5,−1.2)	0.020
MDC	932.34 ± 344.26	877.69 ± 359.04	998.7 ± 325.87	−121 (−133.33,375.34)	0.339	−0.35 (−1.1, 0.4)	−60.28 (−405, 284.4)	0.716
IL-9^	0.56 ± 1.01	0.16 ± 0.34	1.06 ± 1.31	−0.91 (0.14,1.67)	0.024	−0.99 (−1.8, −0.2)	−0.62 (−1.3, 0.1)	0.078
IL-7^	4.28 ± 1.25	3.58 ± 0.8	5.13 ± 1.18	−1.55 (0.82,2.28)	<0.001	−1.57 (−2.4, −0.7)	−1.62 (−2.6, −0.7)	0.002*
IL-8	11.83 ± 30.19	3.86 ± 1.56	21.5 ± 43.78	−17.63 (−7.65,42.92)	0.156	−0.6 (−1.4, 0.2)	−2.19 (−5.7, 1.3)	0.203
MCP-1	172 ± 52.83	164.38 ± 53.2	181.26 ± 52.8	−16.89 (−22.25,56.02)	0.385	−0.32 (−1.1, 0.4)	−7.11 (−68.6, 54.4)	0.810
TNFα	15.88 ± 57.72	23.8 ± 78.09	6.26 ± 1.66	17.54 (−57.7,22.61)	0.368	0.3 (−0.4, 1)	10.69 (−51.9,73.3)	0.722
CRP	0.37 ± 0.46	0.48 ± 0.57	0.24 ± 0.24	0.24 (−0.56,0.08)	0.128	0.53 (−0.2, 1.3)	0.13 (−0.4, 0.7)	0.613
SAP	0.27 ± 0.09	0.26 ± 0.09	0.29 ± 0.11	−0.02 (−0.05,0.09)	0.506	−0.24 (−1,0.5)	−0.06 (−0.2, 0)	0.187

Values are presented as Mean ± SD, and the units are pg/mL, except for CRP and SAP which were measured in ng/mL; IL = interleukin; TGFα = Transforming growth factor alpha; IFNg = Interferon gamma; MDC = Macrophage-derived chemokine; MCP-1 = Monocyte chemoattractant protein −1; TNFα = Tumor necrosis factor alpha; CRP = C-reactive protein; SAP = Serum amyloid P-component. Adjusted mean differences between groups obtained by linear regression model adjusting for number of chronic diseases, education and income. ^{^} Large effect size per Cohen convention.

^*Significant finding, Bonferroni corrected p <.0005.