Table 2.
Correlations between BPH drugs variables and demography-, socioeconomics-, health condition-, and lifestyle habits-related variables
| Category | Variables | Uroselective α1 receptor blockers |
Dutasteride |
|---|---|---|---|
| r with 95% CI | r with 95% CI | ||
| BPH drugs | α1 receptor blockers claim | – | 0.7615 (0.6071 ∼ 0.8605)∗∗ |
| Dutasteride claim | 0.7615 (0.6071 ∼ 0.8605)∗∗ | – | |
| Demography | Age | 0.8961 (0.8199 ∼ 0.9411)∗∗ | 0.6469 (0.4419 ∼ 0.7878)∗∗ |
| Socioeconomics | Population density | −0.4420 (−0.8402 ∼ −0.1774)∗∗ | −0.3359 (−0.7658 ∼ −0.0540)∗ |
| Enrollment rate | −0.4021 (−0.6179 ∼ −0.1300)∗∗ | −0.4545 (−0.6560 ∼ −0.1924)∗∗ | |
| Household income | 0.0830 (−0.2091 ∼ 0.3616) | −0.0617 (−0.3428 ∼ 0.2295) | |
| Number of doctors | −0.0409 (−0.3243 ∼ 0.2492) | −0.1765 (−0.4413 ∼ 0.1165) | |
| Health conditiona | BMI | −0.0947 (−0.3718 - 0.1978) | 0.2769 (−0.0111 ∼ 0.5225) |
| Serum HbA1c | −0.0585 (−0.3400 ∼ 0.2325) | 0.0786 (−0.2134 ∼ 0.3577) | |
| Serum HDL-C | 0.1877 (−0.1051 ∼ 0.4506) | 0.1785 (−0.1145 ∼ 0.4430) | |
| Serum LDL-C | −0.3772 (−0.5994 ∼ −0.1010)∗∗ | −0.2682 (−0.5157 ∼ 0.0205) | |
| Serum ALT | 0.4889 (0.2346 ∼ 0.6805)∗∗ | 0.6814 (0.4902 ∼ 0.8101)∗∗ | |
| Ccr | −0.0347 (−0.3187 ∼ 0.2550) | 0.0406 (−0.2495 ∼ 0.3240) | |
| eGFR | 0.0397 (−0.2503 ∼ 0.3232) | 0.0643 (−0.2271 ∼ 0.3451) | |
| Urine protein | −0.3435 (−0.5740 ∼ −0.0625)∗ | −0.2391 (−0.4924 ∼ 0.0516) | |
| Serum hemoglobin | 0.1749 (−0.1182 ∼ 0.4400) | 0.3336 (0.0513 ∼ 0.5665)∗ | |
| Systolic BP | 0.4772 (0.2202 ∼ 0.6723)∗∗ | 0.3604 (0.0817 ∼ 0.5868)∗ | |
| ECG | −0.0152 (−0.3010 ∼ 0.2732) | 0.1945 (−0.0982 ∼ 0.4562) | |
| Lifestyle habits-related questionsa | Antihypertensive medication | 0.2956 (0.0092 ∼ 0.5372)∗ | 0.5971 (0.3740 ∼ 0.7548)∗∗ |
| Antidiabetic medication | 0.1826 (−0.1104 ∼ 0.4463) | 0.4356 (0.1696 ∼ 0.6424) ∗∗ | |
| Antihyperlipidemic drug | −0.0683 (−0.3487 ∼ 0.2232) | 0.0022 (−0.2851 ∼ 0.2892) | |
| History of stroke | −0.3417 (−0.5727 ∼ −0.0604)∗ | −0.1062 (−0.3817 ∼ 0.1867) | |
| History of heart disease | −0.0041 (−0.2909 ∼ 0.2834) | 0.2781 (−0.0098 ∼ 0.5235) | |
| History of kidney failure | −0.4215 (−0.6322 ∼ −0.1528)∗∗ | −0.2167 (−0.4744 ∼ 0.0751) | |
| History of anemia | −0.3371 (−0.5692 ∼ −0.0553)∗ | −0.3489 (−0.5781 ∼ −0.0686)∗ | |
| Smoking habits | 0.6116 (0.3936 ∼ 0.7645)∗∗ | 0.6598 (0.4598 ∼ 0.7961)∗∗ | |
| Body weight gain | −0.1262 (−0.3989 ∼ 0.1671) | 0.0797 (−0.2123 ∼ 0.3587) | |
| Exercise habits | −0.5696 (−0.7364 ∼ −0.3377)∗∗ | −0.3026 (−0.5426 ∼ −0.0170) ∗ | |
| Walking habits | −0.1450 (−0.4149 ∼ 0.1484) | 0.1573 (−0.1360 ∼ 0.4252) | |
| Walking speed | −0.3412 (−0.5723 ∼ −0.0599)∗ | −0.1222 (−0.3955 ∼ 0.1709) | |
| Chewing condition | −0.1758 (−0.4407 ∼ 0.1173) | 0.2039 (−0.4639 ∼ 0.0885) | |
| Fast eating speed | −0.4091 (−0.6231 ∼ −0.1382)∗∗ | −0.4218 (−0.6324 ∼ −0.1532)∗∗ | |
| Snack habits | −0.1205 (−0.3940 ∼ 0.1727) | −0.3959 (−0.6133 ∼ −0.1226) ∗∗ | |
| Skipping breakfast habits | −0.4116 (−0.6249 ∼ −0.1411)∗∗ | −0.0814 (−0.3601 ∼ 0.2107) | |
| Daily drinking | 0.6001 (0.3781 ∼ 0.7568)∗∗ | 0.4083 (0.1372 ∼ 0.6225) ∗∗ | |
| A small amount of drinking | −0.3725 (−0.5959 ∼ −0.0956)∗∗ | −0.5292 (−0.7087 ∼ −0.2854)∗∗ |
Bold face represents |r| > 0.5 by Pearson's correlation analysis. CI, confidence interval; ∗p < 0.05; ∗∗p < 0.01 by t-test.
a
Values, that are age standardized for the age range of 40–74 years, are used as health condition- and lifestyle-related variables.