Figure 4.

The bivariate posterior for the conformational transition rates ${\lambda }_{esc}$ and FRET efficiencies ${\epsilon }_{FRET}$ for experimental data acquired in the presence of different HJ concentrations. Here, we show our bivariate posteriors where red dots show MAP estimates. In (a), we show the posterior for a sample with 1 mM$\mathrm{M}\mathrm{g}\mathrm{C}{\mathrm{l}}_2$. We report escape rates of ${\mathrm{1,530}}_{-550}^{+500}$ and ${\mathrm{1,240}}_{-420}^{+420}$ s⁻¹ in this case. The posterior for a sample with 3 mM$\mathrm{M}\mathrm{g}\mathrm{C}{\mathrm{l}}_2$ is shown in (b). We report escape rates of ${140}_{-38}^{+38}$ and ${142}_{-32}^{+32}$ s⁻¹ for this case. In (c), we show our posterior for a sample with 5 mM$\mathrm{M}\mathrm{g}\mathrm{C}{\mathrm{l}}_2$. Here, we report escape rates of ${64}_{-9}^{+9}$ and ${80}_{-10}^{+10}$ s⁻¹. The posterior in (d) is for a sample with 10 mM$\mathrm{M}\mathrm{g}\mathrm{C}{\mathrm{l}}_2$. We report escape rates of ${39}_{-12}^{+17}$ and ${41}_{-12}^{+23}$ s⁻¹.