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. 2022 Oct 13;46(1):75–83. doi: 10.1038/s41440-022-01046-4

Table 2.

The association of mean hourly systolic blood pressure between 1 and 24 h with outcomes

Outcome N (%) Crude Adjusted. Model 1 Adjusted. Model 2
Odds ratioa 95% CIa P Odds ratioa 95% CIa P Odds ratioa 95% CIa P
Death or disability 176/495 (35.6%) 1.17 1.00–1.37 0.0507 1.28 1.07–1.52 0.0051 1.25 1.03–1.52 0.0224
    Adding 2 patients without available datab 178/497 (35.8%) 1.17 1.00–1.36 0.0538 1.28 1.08–1.52 0.0050 1.25 1.03–1.52 0.0221
Hematoma expansion 76/486 (15.6%) 1.51 1.22–1.86 0.0001 1.45 1.16–1.81 0.0011 1.49 1.18–1.87 0.0005
    Adding 13 patients with emergent surgeryc 89/499 (17.8%) 1.44 1.18–1.75 0.0003 1.38 1.13–1.68 0.0015 1.40 1.14–1.73 0.0014
Serious adverse events 88/499 (17.6%) 1.07 0.88–1.30 0.5114 1.11 0.90–1.36 0.3418 1.08 0.87–1.34 0.4892
Cardio-renal serious adverse events 7/499 (1.4%) 1.02 0.54–1.92 0.9478

Multivariable analysis is not done for cardio-renal serious adverse events because of a small event number

Model 1: adjusted for sex, age, and study group

Model 2: adjusted for sex, age, study group, baseline systolic blood pressure, baseline National Institutes of Health Stroke Scale score, baseline hematoma volume, lobar hematoma, and onset-to-randomization time

aper 10 mmHg

b2 patients added are regarded as having death or disability

c13 patients added are regarded as having hematoma expansion