Table 2.
Outcome | N (%) | Crude | Adjusted. Model 1 | Adjusted. Model 2 | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Odds ratioa | 95% CIa | P | Odds ratioa | 95% CIa | P | Odds ratioa | 95% CIa | P | ||
Death or disability | 176/495 (35.6%) | 1.17 | 1.00–1.37 | 0.0507 | 1.28 | 1.07–1.52 | 0.0051 | 1.25 | 1.03–1.52 | 0.0224 |
Adding 2 patients without available datab | 178/497 (35.8%) | 1.17 | 1.00–1.36 | 0.0538 | 1.28 | 1.08–1.52 | 0.0050 | 1.25 | 1.03–1.52 | 0.0221 |
Hematoma expansion | 76/486 (15.6%) | 1.51 | 1.22–1.86 | 0.0001 | 1.45 | 1.16–1.81 | 0.0011 | 1.49 | 1.18–1.87 | 0.0005 |
Adding 13 patients with emergent surgeryc | 89/499 (17.8%) | 1.44 | 1.18–1.75 | 0.0003 | 1.38 | 1.13–1.68 | 0.0015 | 1.40 | 1.14–1.73 | 0.0014 |
Serious adverse events | 88/499 (17.6%) | 1.07 | 0.88–1.30 | 0.5114 | 1.11 | 0.90–1.36 | 0.3418 | 1.08 | 0.87–1.34 | 0.4892 |
Cardio-renal serious adverse events | 7/499 (1.4%) | 1.02 | 0.54–1.92 | 0.9478 | — | — |
Multivariable analysis is not done for cardio-renal serious adverse events because of a small event number
Model 1: adjusted for sex, age, and study group
Model 2: adjusted for sex, age, study group, baseline systolic blood pressure, baseline National Institutes of Health Stroke Scale score, baseline hematoma volume, lobar hematoma, and onset-to-randomization time
aper 10 mmHg
b2 patients added are regarded as having death or disability
c13 patients added are regarded as having hematoma expansion