Table A3.
01/01/2015–12/31/2015 | 01/01/2016–12/31/2016 | 01/01/2017–12/31/2017 | 01/01/2018–12/31/2018 |
Linear trend |
||
---|---|---|---|---|---|---|
p-value | direction | |||||
Overall (40 + ) | ||||||
High sensitivity gFOBT (gFOBT) / FIT | 19.82 % | 22.07 % | 19.26 % | 16.88 % | <0.0001 | negative |
mt-sDNA | 3.28 % | 4.90 % | 6.84 % | 10.99 % | <0.0001 | positive |
CT colonography | 0.07 % | 0.11 % | 0.09 % | 0.01 % | <0.05 | negative |
Screening Colonoscopy | 76.71 % | 72.60 % | 73.43 % | 71.67 % | <0.0001 | negative |
Sigmoidoscopy | 0.11 % | 0.32 % | 0.38 % | 0.45 % | <0.0001 | positive |
Aged as of Dec 31st: 40 to 44 | ||||||
High sensitivity gFOBT (gFOBT) / FIT | 29.05 % | 34.55 % | 23.67 % | 18.50 % | <0.01 | negative |
mt-sDNA | 0.48 % | 0.00 % | 0.00 % | 0.00 % | NS | N/A |
CT colonography | 0.00 % | 0.00 % | 0.00 % | 0.00 % | NS | N/A |
Screening Colonoscopy | 70.48 % | 64.63 % | 76.33 % | 79.19 % | <0.01 | positive |
Sigmoidoscopy | 0.00 % | 0.81 % | 0.00 % | 2.31 % | <0.1 | positive |
Aged as of Dec 31st: 45 to 49 | ||||||
High sensitivity gFOBT (gFOBT) / FIT | 31.32 % | 27.35 % | 24.31 % | 18.48 % | <0.0001 | negative |
mt-sDNA | 0.21 % | 0.00 % | 0.00 % | 0.27 % | NS | N/A |
CT colonography | 0.00 % | 0.00 % | 0.00 % | 0.00 % | NS | N/A |
Screening Colonoscopy | 68.27 % | 72.04 % | 75.26 % | 79.89 % | <0.0001 | positive |
Sigmoidoscopy | 0.21 % | 0.61 % | 0.42 % | 1.36 % | <0.1 | positive |
Aged as of Dec 31st: ≥76 | ||||||
High sensitivity gFOBT (gFOBT) / FIT | 35.25 % | 36.23 % | 32.54 % | 30.73 % | <0.01 | negative |
mt-sDNA | 3.10 % | 3.44 % | 5.05 % | 7.18 % | <0.0001 | positive |
CT colonography | 0.13 % | 0.48 % | 0.32 % | 0.00 % | NS | N/A |
Screening Colonoscopy | 61.20 % | 59.13 % | 60.74 % | 61.05 % | NS | N/A |
Sigmoidoscopy | 0.32 % | 0.72 % | 1.34 % | 1.05 % | <0.01 | positive |