Table A4.
CRC Screening Test Mix - Screening Incidence: Overall and by age groups (<50 and > 75 years).
|
Screening incidence for those due for CRC screening, per 1000 |
Screening incidence for all, per 1000 |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 01/01/2015–12/31/2015 | 01/01/2016–12/31/2016 | 01/01/2017–12/31/2017 | 01/01/2018–12/31/2018 |
Linear trend |
01/01/2015–12/31/2015 | 01/01/2016–12/31/2016 | 01/01/2017–12/31/2017 | 01/01/2018–12/31/2018 |
Linear trend |
|||
| p-value | direction | p-value | direction | |||||||||
| Overall (40 + ) | ||||||||||||
| Any screening modality | 101.47 | 109.29 | 108.19 | 103.24 | NS | N/A | 95.70 | 107.46 | 107.17 | 99.78 | NS | N/A |
| High sensitivity gFOBT (gFOBT) | 14.37 | 15.97 | 12.51 | 7.04 | NS | N/A | 14.76 | 17.10 | 13.22 | 8.47 | NS | N/A |
| FIT | 3.39 | 5.97 | 7.31 | 10.47 | <0.05 | positive | 4.21 | 6.61 | 7.41 | 8.37 | <0.05 | positive |
| Mt-sDNA (COLOGUARD) | 4.16 | 7.11 | 10.53 | 16.98 | <0.05 | positive | 3.14 | 5.26 | 7.33 | 10.97 | <0.05 | positive |
| CT colonography (CTC) | 0.07 | 0.08 | 0.05 | 0.00 | NS | N/A | 0.07 | 0.12 | 0.10 | 0.01 | NS | N/A |
| Screening Colonoscopy (SC) | 79.42 | 79.99 | 77.62 | 68.55 | NS | N/A | 73.41 | 78.02 | 78.70 | 71.52 | NS | N/A |
| Sigmoidoscopy (SIG) | 0.07 | 0.16 | 0.17 | 0.20 | <0.1 | positive | 0.10 | 0.35 | 0.41 | 0.45 | <0.1 | positive |
|
Aged as of Dec 31st: 40 to 44 |
||||||||||||
| Any screening modality | 23.76 | 26.39 | 17.98 | 18.80 | NS | N/A | 24.26 | 27.53 | 18.87 | 19.63 | NS | N/A |
| High sensitivity gFOBT (gFOBT) | 4.97 | 6.88 | 3.32 | 2.44 | NS | N/A | 4.97 | 7.16 | 3.35 | 2.50 | NS | N/A |
| FIT | 2.13 | 2.29 | 1.15 | 1.16 | NS | N/A | 2.08 | 2.35 | 1.12 | 1.13 | NS | N/A |
| Mt-sDNA (COLOGUARD) | 0.12 | 0.00 | 0.00 | 0.00 | NS | N/A | 0.12 | 0.00 | 0.00 | 0.00 | NS | N/A |
| CT colonography (CTC) | 0.00 | 0.00 | 0.00 | 0.00 | NS | N/A | 0.00 | 0.00 | 0.00 | 0.00 | NS | N/A |
| Screening Colonoscopy (SC) | 16.55 | 17.10 | 13.52 | 14.85 | NS | N/A | 17.10 | 17.79 | 14.40 | 15.54 | NS | N/A |
| Sigmoidoscopy (SIG) | 0.00 | 0.11 | 0.00 | 0.35 | NS | N/A | 0.00 | 0.22 | 0.00 | 0.45 | NS | N/A |
| Aged as of Dec 31st: 45 to 49 | ||||||||||||
| Any screening modality | 29.22 | 29.69 | 28.10 | 21.96 | NS | N/A | 30.67 | 31.58 | 31.31 | 25.48 | NS | N/A |
| High sensitivity gFOBT (gFOBT) | 7.69 | 5.92 | 5.82 | 3.82 | <0.05 | negative | 7.94 | 6.12 | 6.02 | 3.95 | <0.05 | negative |
| FIT | 1.74 | 2.32 | 1.49 | 0.60 | NS | N/A | 1.66 | 2.51 | 1.59 | 0.76 | NS | N/A |
| Mt-sDNA (COLOGUARD) | 0.07 | 0.00 | 0.00 | 0.07 | NS | N/A | 0.06 | 0.00 | 0.00 | 0.07 | NS | N/A |
| CT colonography (CTC) | 0.00 | 0.00 | 0.00 | 0.00 | NS | N/A | 0.00 | 0.00 | 0.00 | 0.00 | NS | N/A |
| Screening Colonoscopy (SC) | 19.72 | 21.31 | 20.72 | 17.16 | NS | N/A | 20.94 | 22.75 | 23.57 | 20.36 | NS | N/A |
| Sigmoidoscopy (SIG) | 0.00 | 0.14 | 0.07 | 0.30 | NS | N/A | 0.06 | 0.19 | 0.13 | 0.35 | NS | N/A |
| Aged as of Dec 31st: ≥76 | ||||||||||||
| Any screening modality | 70.22 | 68.42 | 60.97 | 54.45 | <0.05 | negative | 75.48 | 79.25 | 74.44 | 68.17 | NS | N/A |
| High sensitivity gFOBT (gFOBT) | 18.69 | 15.64 | 14.21 | 11.07 | <0.01 | negative | 19.30 | 17.96 | 15.52 | 12.11 | <0.05 | negative |
| FIT | 6.70 | 9.78 | 7.31 | 9.67 | NS | N/A | 7.31 | 10.75 | 8.71 | 8.84 | NS | N/A |
| Mt-sDNA (COLOGUARD) | 2.64 | 3.37 | 4.53 | 6.08 | <0.05 | positive | 2.34 | 2.72 | 3.76 | 4.89 | <0.05 | positive |
| CT colonography (CTC) | 0.12 | 0.31 | 0.27 | 0.00 | NS | N/A | 0.10 | 0.38 | 0.24 | 0.00 | NS | N/A |
| Screening Colonoscopy (SC) | 41.84 | 38.95 | 34.17 | 27.34 | <0.05 | negative | 46.19 | 46.86 | 45.22 | 41.61 | NS | N/A |
| Sigmoidoscopy (SIG) | 0.24 | 0.37 | 0.47 | 0.29 | NS | N/A | 0.24 | 0.57 | 1.00 | 0.71 | NS | N/A |