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. 2022 Dec 13;12:21560. doi: 10.1038/s41598-022-26030-3

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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In vitro luciferase expression of Ad-L2 and OAd-tAIB-Luc in the presence of mouse and human serum. Ad-L2 and OAd-tAIB-Luc were pre-incubated with diluted mouse and human serum followed by adding to (A) H1299, (B) HeLa, and (C) PANC-1 cells at 200 VP/cell. Luciferase activities were measured 3 days after virus treatment. The luminescence levels in the cells without pre-incubation with human serum were normalized to 100%. These data are expressed as the means ± S.D. (n = 4).