Table 1.

Fractional tumor volume (FTV) after treatment with C-REV, either alone or in combination with metformin.

Injected side						Contralateral side
	FTV	FTV	E-FTV	O-FTV	E-FTV/O-FTVa		FTV	FTV	E-FTV	O-FTV	E-FTV/O-FTVa
Days	C-REV	Met	Comb	Comb	Comb	Days	C-REV	Met	Comb	Comb	Comb
0	0.97103129	0.88412514	0.85851318	0.86906141	0.9878625	0	1.1159601	1.0286783	1.14796394	1.09600998	1.04740282
3	0.67217525	0.68985396	0.46370276	0.47386626	0.97855197	3	0.78076923	0.91846154	0.71710651	0.54192308	1.32326254
6	0.66928952	0.71765795	0.48032094	0.36241611	1.32533001	6	0.65195566	0.83078854	0.54163729	0.38883079	1.39298971
9	0.6487931	0.77431034	0.50236721	0.35506897	1.41484405	9	0.55093712	0.71659613	0.39479941	0.35	1.12799831
14	0.5735134	0.67730342	0.38844258	0.34741886	1.11808144	14	0.5846316	0.71078833	0.41554932	0.36066534	1.15217427

FTV, fractional tumor volume (mean tumor volume experimental/mean tumor volume control); E- FTV, expected FTV (mean FTV of C-REV) × (mean FTV of metformin); O-FTV, observed FTV.

^aSynergic effect: E-FTV/O-TV>1 in bold.