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. 2022 Dec 13;5:1367. doi: 10.1038/s42003-022-04075-4

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Types of genes are identified by color and positioning in the Cytoscape graph. Gene interactions from miRNet databases are denoted by gray lines. lncRNA are on the left, miRNA in the center, and differentially expressed protein-coding genes from each of the four cancer driver pathways are on the right side of the graph. b Positive LFC (purple) denotes higher expression in CCLE. Negative LFC (green) denotes higher expression in TCGA.