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. 2022 Dec 13;12:21561. doi: 10.1038/s41598-022-25783-1

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Mean light luminance polarity shift for OFF preferential RGCs is altered upon glial BMAL1 deletion. (a) Polarity maintenance was calculated as the percentage of cells within the ON, ON–OFF, and OFF subtypes that did not change their polarity preference at different ambient illumination in Ctrl and Bmal1cKO (Fisher’s exact test to assess the difference between groups). (b) The analysis in (a) has been performed only for ON and OFF RGCs at different ZTs collected from 37 datasets. Significance asterisks are displayed for Ctrl and Bmal1cKO comparison. *P < 0.05; ****P < 0.0001; ns = not significant.