Table 1.
Number of studies, publication rate and number of patients in completed studies on pediatric dialysis registered at ClinicalTrials.gov
| Characteristic | Number of studies | Results available (% of number of studies) |
Peer-reviewed results (% of number of studies) |
Patient number enrolled | Patient number enrolled in studies with available results (% of patient number enrolled) |
|---|---|---|---|---|---|
| All studies | 53 | 28 (52.8) | 19 (35.8) | 7287 | 4025 (55.2) |
| Pediatric studies, n (% of 53) | 12 (22.6) | 9 (75.0) | 6 (50.0) | 616 | 542 (87.9) |
| Research topics (% of 53) | |||||
| Medication and control of secondary complications | 26 (49.1) | 13 (50.0) | 7 (26.9) | 2869 | 1324 (46.1) |
| Dialysis technique and dialysis efficiency | 20 (37.7) | 11 (55.0) | 8 (40.0) | 1965 | 639 (32.5) |
| Others | 7 (13.2) | 4 (57.1) | 4 (57.1) | 2453 | 2062 (84.1) |
| Study design, n (% of 53) | |||||
| Randomized controlled trials | 14 (26.4) | 9 (64.3) | 8 (57.1) | 621 | 398 (64.1) |
| Non-randomized interventional trials | 18 (33.9) | 12 (66.7) | 7 (38.9) | 1376 | 1155 (83.9) |
| Observational studies | 21 (39.6) | 7 (33.3) | 4 (19.0) | 5290 | 2472 (46.7) |
| Type of funding, n (% of 53) | |||||
| Co-funded by industry | 25 (47.1) | 15 (60.0) | 9 (36.0) | 4725 | 3474 (73.5) |
| Funded by academia | 28 (52.8) | 13 (46.4) | 10 (35.7) | 2562 | 551 (21.5) |