Table 1.
Comparative incidence of recurrent genetic abnormalities in mexicans, hispanics and non-hispanics children diagnosed with pre-b all.
| Mexicans National Institute of Pediatrics (26, 27, 29,30) | Mexicans Other Institutions (31,32) | Hispanics (22,30) | Non- Hispanics (22, 30) | |
|---|---|---|---|---|
| Translocation Profiles (%) | ||||
| t(12;21) ETV6::RUNX1 | 8.4 | 10.5-14.9 | 12.6 | 24 |
| t(1;19) TCF3::PBXI | 7.2 | 5.8-7.7 | – | – |
| t(17;19) TCF3::HLF | 0.6 | – | – | – |
| 19p13 TCF3 | – | – | 4.6 | 4.7 |
| t(4;11) KMT2A::AFFI | 1.4 | 2.8-4.2 | – | – |
| 11q23 KMT2A | 2.2 | – | 2 | 2.9 |
| t(9;22) BCR::ABLI | 3.7 | 3.3-7.3 | 1.3 | 0.7 |
| Ploidy Level (%) | ||||
| Hyperdiploid | ||||
| >50 | 25.3 | – | 41.1 | 36.6 |
| 47-50 | 16 | – | 13.9 | 18.6 |
| Hypodiploid | ||||
| 41-45 | 8.6 | – | 6 | 8.5 |
| B-Other Abnormalities (%) | ||||
| CRLF2 Rearrangements P2RY8-CRLF2 | 20.5 | – | 5.5 | 8 |
| IGH-CRLF2 | 9.6 | – | 12 | 2.7 |
| iAMP21 | 10.1 | – | – | – |