Table 2.
Clinical demographics of the subjects in the study.
| Variable | AD | HC | p-value* |
|---|---|---|---|
| (n = 12) | (n = 12) | ||
| Male/Female | 3/9 | 3/9 | – |
| Age (years) | – | ||
| Mean ± standard deviation | 69.06 ± 8.56 | 63.76 ± 6.05 | |
| Median (Minimum–Maximum) | 71.44 (51.94–83.98) | 65.21 (52.6–75.5) | |
| MMSE | |||
| Mean ± standard deviation | 18.91 ± 4.08 | 28.17 ± 1.90 | < 0.001 |
| Median (Minimum–Maximum) | 18 (13–27) | 28 (23–30) | |
| MOCA | < 0.001 | ||
| Mean ± standard deviation | 15.58 ± 4.76 | 26.75 ± 3.33 | |
| Median (Minimum–Maximum) | 17.5 (9–24) | 28 (19–30) | |
| Delayed Memory | < 0.001 | ||
| Mean ± standard deviation | 52.25 ± 13.21 | 105.08 ± 14.43 | |
| Median (Minimum–Maximum) | 48 (40–84) | 105.5 (81–126) | |
| Visuo spatial function | 0.004 | ||
| Mean ± standard deviation | 81.17 ± 19.83 | 106.08 ± 19.64 | |
| Median (Minimum–Maximum) | 85.5 (50–116) | 108.5 (64–126) | |
| Attention | 0.001 | ||
| Mean ± standard deviation | 76.25 ± 18.97 | 105.42 ± 13.69 | |
| Median (Minimum–Maximum) | 77 (49–109) | 104.5 (82–135) | |
| Language | < 0.001 | ||
| Mean ± standard deviation | 71.75 ± 15.67 | 95.17 ± 10.22 | |
| Median (Minimum–Maximum) | 76.5 (44–88) | 92 (83–113) | |
| Fazekas score (periventricular) | 0.435 | ||
| Mean ± standard deviation | 1.75 ± 0.97 | 1.33 ± 0.49 | |
| Median (Minimum–Maximum) | 1 (1–3) | 1 (1–2) | |
| Fazekas score (deep white matter) | 0.238 | ||
| Mean ± standard deviation | 1.42 ± 0.67 | 1 ± 0.60 | |
| Median (Minimum–Maximum) | 1 (1–3) | 1 (0–2) |
*Two groups are compared using Mann-Whitney U-test.
AD, Alzheimer's disease; HC, healthy controls; MMSE, Mini-Mental State Examination; MoCA, Montreal Cognitive Assessment.