Skip to main content
. 2022 Nov 30;13:1038735. doi: 10.3389/fneur.2022.1038735

Table 6.

Associations between sleep parameters and computed product (Aβ42 × T-Tau).

Variable (events/h) Beta coefficient
(95% confidence interval)
Oximetry parameters
    ODI-3% (events/h) 0.41 (0.08 to 0.74)*
SDB indices (events/h)
    AHI 0.40 (0.06 to 0.74)*
    AI 0.21 (−0.12 to 0.54)
     AINREM 0.20 (−0.13 to 0.54)
     AIREM 0.19 (−0.16 to 0.54)
    HI 0.35 (−0.03 to 0.72)
     HINREM 0.36 (−0.0 to 0.72)
     HIREM 0.17 (−0.25 to 0.59)
Arousal indices (events/h)
    ArI 0.26 (−0.07 to 0.59)
     ArINREM 0.26 (−0.06 to 0.59)
     ArIREM 0.08 (−0.3 to 0.45)
    Sp-ArI −0.11 (−0.46 to 0.24)
     Sp-ArINREM −0.12 (−0.47 to 0.23)
     Sp-ArIREM −0.12 (−0.46 to 0.21)
    R-ArI 0.34 (0.02 to 0.66)*
     R-ArINREM 0.35 (0.04 to 0.67)*
     R-ArIREM 0.13 (−0.24 to 0.51)

ODI-3%, oxygen desaturation index ≥3%; SDB, sleep-disordered breathing; AHI, apnea–hypopnea index; AI, apnea index; AINREM, apnea index in the non-rapid eye movement stage; AIREM, apnea index in rapid eye movement stage; HI, hypopnea index; HINREM, hypopnea index in non-rapid eye movement stage; HIREM, hypopnea index in rapid eye movement stage. ArI, arousal index; ArINREM, arousal index in non-rapid eye movement stage; ArIREM, arousal index in rapid eye movement stage; Sp-ArI, spontaneous arousal index; Sp-ArINREM, spontaneous arousal index in non-rapid eye movement stage; Sp-ArIREM, spontaneous arousal index in rapid eye movement stage; R-ArI, respiratory arousal index; R-ArINREM, respiratory arousal index in non-rapid eye movement stage; R-ArIREM, respiratory arousal index in rapid eye movement stage.

Multivariable linear regression models were adjusted for age, sex, and body mass index.

*

p < 0.05.