TABLE 3.

Sensitivity analysis–Leave-one-out approach.

Outcome (number of studies in the main/sensitivity analysis)	Main analysis	Sensitivity analysis
Any appropriate ICD therapy (6/5)	OR 0.53 (95% CI 0.33–0.83), p = 0.005	OR 0.52 (95% CI 0.29–0.92), p = 0.02
ICD shocks (8/7)	0.52 (95% CI 0.35–0.77), p = 0.001	0.46 (95% CI 0.30–0.71), p = 0.0004
All-cause mortality (8/7)	OR 0.91 (95% CI 0.58–1.45), p = 0.70	OR 0.88 (95% CI 0.47–1.66), p = 0.70
VT storm (6/5)	OR 0.58 (95% CI 0.39–0.85), p = 0.006	OR 0.51 (95% CI 0.29–0.90), p = 0.02
Cardiovascular mortality (8/7)	OR 0.78 (95% CI 0.49–1.22), p = 0.27	OR 0.69 (95% CI 0.36–1.33), p = 0.27
Cardiovascular hospitalizations (7/6)	OR 0.67 (95% CI 0.49–0.92), p = 0.01	OR 0.64 (95% CI 0.43–0.95), p = 0.03
Complications (8/7)	OR 1.00 (95% CI 0.44–2.27), p = 1.00	OR 1.28 (95% CI 0.50–3.32), p = 0.61
QoL physical component (3/2)	MD −1.02 (95% CI −3.60 to +1.56), p = 0.44	MD −1.30 (95% CI −4.85 to +2.25), p = 0.47
QoL mental component (3/2)	MD 0.31 (95% CI −2.43 to +3.04), p = 0.83	MD 1.11 (95% CI −2.49 to +4.72), p = 0.54

CI, confidence interval; ICD, implantable cardioverter-defibrillator; MD, mean difference; OR, odds ratio; QoL, quality of life; VT, ventricular tachycardia.