TABLE 5.
Genotype, allele or haplotype frequency of the selected gene variants in the area below and above the trend lines of the IgG and NAbs distribution in the whole cohort.
IgG | TP53 rs1042522 | ABO rs657152 | APOE rs7412/rs429358 | ACE2 rs2285666 | HLA-A rs2571381/rs2499 | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
GG | GC | CC | TT | GT | GG | 4 | 3 | G | A | CC/GG | CT/GT | |
Low | 0.183 | 0.348 | 0.469 | 0.052 | 0.478 | 0.469 | 0.226 | 0.774 | 0.774 | 0.226 | 0.78 | 0.22 |
High | 0.05 | 0.35 | 0.60 | 0.15 | 0.475 | 0.375 | 0.075 | 0.925 | 0.632 | 0.368 | 0.90 | 0.10 |
P -genotype | 0.018 | 0.05 | — | — | — | |||||||
P -recessive | 0.0064 | 0.02 | — | — | — | |||||||
P -dominant | 0.07 | 0.18 | — | — | — | |||||||
P -allele | 0.0054 | 0.045 | — | 0.03 | — | |||||||
P -haplotype | — | — | 0.005 | — | 0.04 |
NAbs | TP53 rs1042522 | ABO rs657152 | APOE rs7412/rs429358 | ACE2 rs2285666 | HLA-A rs2571381/rs2499 | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
GG | GC | CC | TT | GT | GG | 4 | 3 | G | A | CC/GG | CT/GT | |
Low | 0.190 | 0.343 | 0.467 | 0.057 | 0.562 | 0.381 | 0.238 | 0.762 | 0.791 | 0.209 | 0.79 | 0.21 |
High | 0.056 | 0.322 | 0.622 | 0.133 | 0.387 | 0.48 | 0.078 | 0.922 | 0.634 | 0.366 | 0.91 | 0.09 |
P -genotype | 0.009 | 0.02 | — | — | — | |||||||
P -recessive | 0.004 | 0.06 | — | — | — | |||||||
P -dominant | 0.03 | 0.12 | — | — | — | |||||||
P -allele | 0.0017 | 0.73 | — | 0.016 | — | |||||||
P -haplotype | — | — | 0.0025 | — | 0.03 |
Low and High, indicate the genotype distribution (frequency) below and above the IgG and NAbs, trend lines respectively. P-genotype, P-recessive, P-dominant, P-allele, P-haplotype indicate the statistical assessment according to the comparison model applied: genotype distribution, recessive, dominant, allelic, or haplotype respectively.