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. 2022 Dec 13;13:7705. doi: 10.1038/s41467-022-35031-9

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — Differential expression analyses (a) and Hallmark gene set enrichment analyses (b) are conducted for four large cell clusters in the BMNC dataset based on the clustering result of scMDC. In panel (a), the dot size shows the expression percentage of a gene in a cell type, and colors show the average expression level of a gene in a cell type with blue as low and red as high.