Figure 2.
Expression profiles of DNM1 transcripts from Ensembl in 39 pediatric brain tissue samples
(A) Individual transcript expression, highlighting identifiable transcripts within RefSeq. Bars represent individual samples.
(B) Proportional transcript expression for transcripts containing exon 10a and exon 10b versus age, showing age and expression are not strongly correlated.
(C) Cumulative expression per individual of full-length DNM1 transcripts containing exon 10a (blue) or exon 10b (green). DNM1a has markedly higher expression than DNM1b in the pediatric brain. Proportional transcript expression was computed by quantifying transcripts in TPM, classifying by 10th exon, and normalizing to the total TPM across all DNM1 transcripts. All data are reported as ratios.