Table 2. Expression of the serum biomarkers between none-LA Dilation and LA dilation groups.

Biomarkers	No-LA dilation (n = 58)	LA dilation (n = 42)	P-value
Data are expressed as median (quartile range) or mean ± SD. apoA1: apolipoprotein A1; apoB: apolipoprotein B; BUN: blood urea nitrogen; eGFR: estimated glomerular filtration rate; FBG: fasting blood-glucose; HDL-C: high density lipoprote in cholesterol; IVS: interventricular septum; LA: left atrium; LDL-C: low density lipoprotein cholesterol; Lp(a): lipoprotein (a); LAD: left atrium diameter; LVEDD: left ventricular end systolic diameter; LVESD: left ventricular end systolic diameter; RAD: right atrium diameter; RVD: right ventricle diameter; Scr: creatinine; TC: total cholesterol; TG: triglyceride; UA: uric acid; VLDL-C: very low-density lipoprotein cholesterol. P < 0.05 has statistically significant.
TC, mmol/L			0.320
TG, mmol/L	1.15 (0.85, 1.55)	1.16 (0.86, 1.50）	0.780
HDL-C, mmol/L			0.420
LDL-C, mmol/L	2.71 (2.43, 3.32)	2.89 (2.21, 3.81)	0.301
VLDL-C, mmol/L	0.45 (0.31, 0.64)	0.45 (0.35, 0.72)	0.446
Lp(a), mg/L	207.40 (110.95, 366.30)	263.18 (123.05, 562.00)	0.172
apoA1, g/L			0.613
apoB, g/L			0.361
MiR-21	6.05 (3.81, 8.95)	8.02 (5.21, 14.39)	0.011
FBG, mmol/L	5.00 (4.42, 5.63)	5.01 (4.62, 5.57)	0.620
BUN, mmol/L	4.75 (4.00, 5.80)	4.60 (3.64, 6.13)	0.603
Scr, mol/L	70.40 (64.45,80.15)	63.9 (60.1, 73.43)	0.020
UA, mol/L	301.75 (240.05, 337.95)	294.45 (252.36, 330.26)	0.986
eGFR, mL/min	82.18 (70.77, 90.13)	83.29 (71.64, 87.92)	0.771
LAD, mm	35.00 (33.00,37.00)	40.00 (39.00, 42.25)	< 0.001
IVS, mm	10.00 (9.00, 11.00)	10.00 (9.00, 11.00)	0.827
RAD, mm	30.00 (28.00, 31.00)	30.00 (28.75, 32.00)	0.332
RVD, mm	28.00 (27.00,30.00)	30.00 (28.00, 31.00)	0.102
LVESD, mm	29.00 (27.00, 30.00)	28.50 (27.00, 31.00)	0.561
LVEDD, mm	45.00 (42.00, 48.00)	47.00 (43.00, 48.00)	0.422
LVEF			0.001