Table 3.

Determinants for HBV by the presence of different sex using multivariable logistic regression analysis.

Variables	Male (n = 43,636)			Female (n = 77,785)
	Multivariable			Multivariable
	OR	95% CI	p	OR	95% CI	p	Interaction p
Age (per 1 year)	0.998	0.995–1.001	0.172	1.004	1.001–1.007	0.002	<0.001
DM	0.772	0.672–0.886	<0.001	0.872	0.760–1.001	0.052	0.162
Hypertension	0.876	0.804–0.954	0.002	0.855	0.783–0.933	<0.001	0.203
Alcohol history	1.025	0.950–1.107	0.522	1.053	0.913–1.214	0.481	0.845
Smoking history	1.013	0.955–1.075	0.661	0.957	0.883–1.037	0.280	0.269
Body mass index (per 1 kg/m2)	0.990	0.981–0.999	0.029	1.015	1.007–1.022	<0.001	<0.001
Fasting glucose (per 1 mg/dL)	0.999	0.998–1.001	0.461	0.998	0.997–1.000	0.067	0.492
Triglyceride (per 1 mg/dL)	0.998	0.997–0.998	<0.001	0.997	0.997–0.997	<0.001	0.741
Total cholesterol (per 1 mg/dL)	0.995	0.994–0.996	<0.001	0.997	0.996–0.998	<0.001	0.002
AST (per 1 U/L)	1.006	1.003–1.009	<0.001	1.010	1.006–1.014	<0.001	0.024
ALT (per 1 U/L)	1.010	1.008–1.012	<0.001	1.008	1.006–1.010	<0.001	0.157
eGFR (per 1 mL/min/1.73 m2)	0.998	0.996–0.999	0.009	0.997	0.996–0.998	<0.001	0.012
Uric acid (per 1 mg/dL)	0.928	0.906–0.950	<0.001	0.922	0.900–0.946	<0.001	0.239

Values expressed as odds ratio (OR) and 95% confidence interval. HBV, hepatitis B virus; HCV, hepatitis C virus; DM, diabetes mellitus; AST, aspartate aminotransferase; ALT, alanine aminotransferase; eGFR, estimated glomerular filtration rate. Covariates in the multivariable model included age, diabetes, hypertension, alcohol and smoking history, body mass index, fasting glucose, triglyceride, total cholesterol, AST, ALT, eGFR and uric acid.