Table 4.
Determinants for HCV by the presence of different sex using multivariable logistic regression analysis.
| Variables | Male (n = 43,636) | Female (n = 77,785) | |||||
|---|---|---|---|---|---|---|---|
| Multivariable | Multivariable | ||||||
| OR | 95% CI | p | OR | 95% CI | p | Interaction p | |
| Age (per 1 year) | 1.025 | 1.018–1.031 | <0.001 | 1.055 | 1.049–1.061 | <0.001 | <0.001 |
| DM | 0.962 | 0.757–1.222 | 0.751 | 0.821 | 0.650–1.038 | 0.099 | 0.233 |
| Hypertension | 0.908 | 0.765–1.077 | 0.267 | 1.009 | 0.872–1.168 | 0.902 | 0.010 |
| Alcohol history | 1.616 | 1.394–1.872 | <0.001 | 1.447 | 1.129–1.855 | 0.004 | 0.852 |
| Smoking history | 1.302 | 1.132–1.497 | <0.001 | 1.473 | 1.259–1.724 | <0.001 | 0.445 |
| Body mass index (per 1 kg/m2) | 0.982 | 0.963–1.002 | 0.084 | 0.997 | 0.983–1.012 | 0.687 | 0.151 |
| Fasting glucose (per 1 mg/dL) | 1.004 | 1.002–1.007 | <0.001 | 0.999 | 0.996–1.002 | 0.506 | 0.031 |
| Triglyceride (per 1 mg/dL) | 0.999 | 0.998–1.000 | 0.026 | 1.000 | 0.999–1.000 | 0.293 | 0.127 |
| Total cholesterol (per 1 mg/dL) | 0.990 | 0.988–0.992 | <0.001 | 0.991 | 0.990–0.992 | <0.001 | 0.119 |
| AST (per 1 U/L) | 1.008 | 1.004–1.012 | <0.001 | 1.016 | 1.010–1.021 | <0.001 | 0.177 |
| ALT (per 1 U/L) | 1.005 | 1.003–1.008 | <0.001 | 1.001 | 0.997–1.005 | 0.567 | 0.949 |
| eGFR (per 1 mL/min/1.73 m2) | 0.998 | 0.994–1.001 | 0.229 | 1.000 | 0.998–1.003 | 0.689 | 0.055 |
| Uric acid (per 1 mg/dL) | 0.997 | 0.948–1.049 | 0.908 | 1.092 | 1.041–1.145 | <0.001 | 0.001 |
Values expressed as odds ratio (OR) and 95% confidence interval. HBV, hepatitis B virus; HCV, hepatitis C virus; DM, diabetes mellitus; AST, aspartate aminotransferase; ALT, alanine aminotransferase; eGFR, estimated glomerular filtration rate. Covariates in the multivariable model included age, diabetes, hypertension, alcohol and smoking history, body mass index, fasting glucose, triglyceride, total cholesterol, AST, ALT, eGFR and uric acid.