TABLE 2.

Activity of full-length peptides against gram-negative and gram-positive bacteria^a

Peptide	MIC (μM) for:
	E. coli DH5α		E. coli ML-35p		P. aeruginosa PAO1		P. aeruginosa MR3007		MRSA ATCC 33591		S. aureus 930918-3
	Low	High	Low	High	Low	High	Low	High	Low	High	Low	High
mCRAMP	0.25	0.53	0.80	0.67	0.37	0.60	1.29	1.78	2.42	17.9	1.06	2.06
rCRAMP	0.54	0.61	1.55	0.66	0.69	1.17	2.01	1.78	3.19	>20.1	2.14	2.16
SMAP34	0.50	0.23	1.93	1.03	0.60	0.77	2.00	1.91	4.00	13.3	1.96	2.13
SMAP29	0.10	0.07	0.18	0.12	0.17	0.08	0.34	0.18	1.24	0.65	0.31	0.43
CAP 18	0.19	0.21	0.05	0.09	0.20	0.62	0.05	0.36	1.24	1.36	0.41	0.63
FALL39	0.16	0.20	1.68	0.93	0.49	0.69	1.78	1.29	6.90	>16.8	4.25	5.48
LL37	0.19	0.44	1.20	0.58	0.54	1.03	0.53	1.54	5.45	30.8	3.58	2.58

^aData are MICs determined by the radial-diffusion assay with low-salt (no NaCl) and high-salt (100 mM NaCl) underlays.