TABLE 2.
Percent reduction in the presence of middle ear effusions compared to identically challenged controls
| Day postchallengea | % Reductionb
|
|||||||
|---|---|---|---|---|---|---|---|---|
| Study A
|
Study B
|
|||||||
| LB1– 86-028NP | LPD-LB1(f)2,1,3– 86-028NP | LB1- 1885MEE | LPD-LB1(f)2,1,3– 1885MEE | LB1– 86-028NP | LPD-LB1(f)2,1,3– 86-028NP | LB1- 1728MEE | LPD-LB1(f)2,1,3– 1728MEE | |
| 9 | 100∗ | 100∗ | ||||||
| 10 | 100∗ | 60 | 100∗ | 87∗ | ||||
| 11 | 100∗ | 50 | 100∗ | 90∗ | ||||
| 12 | 100∗ | 71 | 76 | 87∗ | ||||
| 13 | 100∗ | 92∗ | 100∗ | 100∗ | 100∗ | 83∗ | 76 | 76 |
| 14 | 100∗ | 100∗ | 77 | 100∗ | 100∗ | 100∗ | 51 | 76 |
| 15 | 100∗ | 100∗ | 77 | 100∗ | ||||
| 16 | 100∗ | 100∗ | 81 | 100∗ | ||||
| 17 | 100∗ | 100∗ | 100∗ | 93∗ | ||||
| 18 | 100∗ | 100∗ | 100∗ | 84∗ | ||||
| 19 | 100∗ | 100∗ | ||||||
| 20 | 100∗ | 100∗ | ||||||
| 21 | 100∗ | 100∗ | ||||||
Day after bacterial challenge when >50% of the ears in the sham cohort had effusions.
∗, Significance set at P ≤0.01.