TABLE 5.
Accuracy of echocardiographic indices in LAAT prediction according to CHA2DS2-VASc score values.
| Parameters | AUC | Characteristics (%) |
Predictive value (%) |
OR 95% | p a | ||
| Sensitivity | Specificity | Positive | Negative | ||||
| Subgroup A (CHA2DS2-VASc 0–1 point) | |||||||
| LVEF/LAA ≤ 1.5 | 0.92 | 89 | 89 | 100 | 17 | 29 [5.9–145] | <0.001 |
| LVEF/LAVI ≤ 0.7 | 0.78 | 92 | 60 | 98 | 21 | 18 [4.7–68] | <0.001 |
| LVEF ≤ 48% | 0.72 | 85 | 62 | 99 | 9 | 9 [2.8–25] | <0.001 |
| LAD ≥ 41 mm | 0.74 | 37 | 100 | 100 | 4 | 15 [0.9–264] | 0.003 |
| LAA ≥ 26 cm2 | 0.79 | 62 | 100 | 100 | 6 | 29 [1.7–511] | <0.001 |
| Subgroup B (CHA2DS2-VASc 2–3 points) | |||||||
| LVEF/LAA ≤ 1.5 | 0.77 | 78 | 72 | 97 | 22 | 9 [5–16.2] | <0.001 |
| LVEF/LAVI ≤ 0.9 | 0.75 | 77 | 67 | 96 | 21 | 6.6 [3.5–12.2] | <0.001 |
| LVEF ≤ 47% | 0.76 | 74 | 68 | 96 | 19 | 5.9 [3.7–10] | <0.001 |
| LAD ≥ 45 mm | 0.67 | 53 | 74 | 96 | 12 | 3.2 [1.87–5.2] | <0.001 |
| LAA ≥ 29 cm2 | 0.67 | 69 | 58 | 95 | 14 | 3.1 [1.8–5.1] | <0.001 |
| Subgroup C (CHA2DS2-VASc 4 and more points) | |||||||
| LVEF/LAA ≤ 2.0 | 0.70 | 43 | 87 | 96 | 17 | 4.3 [2.5–7.4] | <0.001 |
| LVEF/LAVI ≤ 0.9 | 0.69 | 70 | 64 | 94 | 20 | 3.7 [2.3–6.1] | <0.001 |
| LVEF ≤ 55% | 0.70 | 38 | 92 | 98 | 15 | 7.7 [3.7–14.3] | 0.001 |
| LAD ≥ 44 mm | 0.55 | 39 | 72 | 92 | 13 | 1.7 [1.1–2.5] | 0.019 |
| LAA ≥ 29 cm2 | 0.55 | 29 | 82 | 92 | 13 | 1.8 [1.1–3.1] | 0.02 |
ap-values refer for the differences between LAAT (+) and LAAT (-) groups.
AUC, an area under the curve; LAA, left atrial area; LAD, left atrial diameter; LAAT, left atrial thrombus; LVEF, left ventricular ejection fraction; OR, odds ratio.