Skip to main content
. 2022 Nov 30;9:1059111. doi: 10.3389/fcvm.2022.1059111

TABLE 5.

Accuracy of echocardiographic indices in LAAT prediction according to CHA2DS2-VASc score values.

Parameters AUC Characteristics (%)
Predictive value (%)
OR 95% p a
Sensitivity Specificity Positive Negative
Subgroup A (CHA2DS2-VASc 0–1 point)
LVEF/LAA ≤ 1.5 0.92 89 89 100 17 29 [5.9–145] <0.001
LVEF/LAVI ≤ 0.7 0.78 92 60 98 21 18 [4.7–68] <0.001
LVEF ≤ 48% 0.72 85 62 99 9 9 [2.8–25] <0.001
LAD ≥ 41 mm 0.74 37 100 100 4 15 [0.9–264] 0.003
LAA ≥ 26 cm2 0.79 62 100 100 6 29 [1.7–511] <0.001
Subgroup B (CHA2DS2-VASc 2–3 points)
LVEF/LAA ≤ 1.5 0.77 78 72 97 22 9 [5–16.2] <0.001
LVEF/LAVI ≤ 0.9 0.75 77 67 96 21 6.6 [3.5–12.2] <0.001
LVEF ≤ 47% 0.76 74 68 96 19 5.9 [3.7–10] <0.001
LAD ≥ 45 mm 0.67 53 74 96 12 3.2 [1.87–5.2] <0.001
LAA ≥ 29 cm2 0.67 69 58 95 14 3.1 [1.8–5.1] <0.001
Subgroup C (CHA2DS2-VASc 4 and more points)
LVEF/LAA ≤ 2.0 0.70 43 87 96 17 4.3 [2.5–7.4] <0.001
LVEF/LAVI ≤ 0.9 0.69 70 64 94 20 3.7 [2.3–6.1] <0.001
LVEF ≤ 55% 0.70 38 92 98 15 7.7 [3.7–14.3] 0.001
LAD ≥ 44 mm 0.55 39 72 92 13 1.7 [1.1–2.5] 0.019
LAA ≥ 29 cm2 0.55 29 82 92 13 1.8 [1.1–3.1] 0.02

ap-values refer for the differences between LAAT (+) and LAAT (-) groups.

AUC, an area under the curve; LAA, left atrial area; LAD, left atrial diameter; LAAT, left atrial thrombus; LVEF, left ventricular ejection fraction; OR, odds ratio.