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. 2022 Nov 30;13:1050906. doi: 10.3389/fgene.2022.1050906

FIGURE 5.

FIGURE 5

Placenta autophagy-related protein expression and ultrastructure in NCs and patients with GDM. (A) The expression of the autophagy-related proteins LC3-I, LC3-II, p62, and ATG5 was determined by western blotting. (B) TEM of NC and GDM placental tissues. Integrated and clear organelles, such as mitochondria (asterisks) and the endoplasmic reticulum (number signs), were present, but autophagosomes were not seen in NC samples. The GDM placentas showed obvious autolysosome structures (black arrowheads), and partially degraded mitochndria were visible in the autophagolysosomes (red dotted line).