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. 2022 Nov 30;13:1050906. doi: 10.3389/fgene.2022.1050906

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Copyright © 2022 Bao, Zhang, Liu, Wu and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Prediction of the autophagy-associated circCDH2-miRNA-mRNA interaction network. (A) GO analysis of the autophagy-related terms of circRNA traget genes. (B) A circCDH2-miRNA-mRNA interaction network was predicted using bioinformatics online programs (starBase, circBase, TargetScan, and miRBase). Yellow indicates circCDH2, purple indicates miRNA, and red indicates the target gene. (C) The predicted binding sites between circCDH2-miR-33b-3p and miR-33b-3p-ULK1 are shown. The 7mer-m8 was an exact match to positions 2–8 of the mature miRNA (seed + position 8), and the 8mer was an exact match to positions 2–8 of the mature miRNA (seed + position 8) followed by a “G”.