Fig. 1.
A) Representative sample (2 muscles of 1 mouse) showing flow cytometry analysis of CD45+ cells isolated from TA muscle from MaFIA mice injected with intramuscular AP20187 (green) versus intramuscular vehicle control (grey). B) Representative sample (1 mouse muscle per panel) demonstrating flow cytometry analysis demonstrating the appearance of a large population of CD45intermediate cells in AP20187 treatment compared to vehicle control treated muscle. C) Cell counts of the CD45intermediate population in AP20187 treated versus vehicle control treated muscle. This experiment is representative of two independent experiments and n = 4. *p = 0.03 by Mann-Whitney test.