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. Author manuscript; available in PMC: 2023 Mar 21.
Published in final edited form as: Nature. 2022 Sep 21;609(7929):1012–1020. doi: 10.1038/s41586-022-05208-9

Extended Data Figure 1. Transcriptional atlas of the fetal human cerebellum.

Extended Data Figure 1.

(a) Schematic summary of the molecular datasets utilized to interconnect murine and human cerebellar profiles with MB. Single-cell and bulk sample counts for each data source are indicated. (b,c) UMAP plots showing published cell-type annotation (b) and predicted cell cycle phase (c) of the fetal human cerebellar atlas8. (d) Correlation heatmap of human cerebellar cell types. (e) Violin plots showing expression of cerebellar lineage markers in the fetal human cerebellar atlas. (f) Inferred cerebellar cell-type proportions in deconvoluted bulk MB transcriptomes. (g) Proportion of cerebellar lineage-associated genes up-regulated in MB subgroups. (h) MB subgroup-specific gene set enrichment in cerebellar cell types.