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. 2022 Dec 13;10(12):e005088. doi: 10.1136/jitc-2022-005088

Figure 2.

Figure 2

High levels of SP140 in HNSCC tumors are associated with higher expression of proapoptotic markers and favorable survival in HNSCC. (A–D) HNSCC TCGA tumors with available protein expression data (n=212) were divided to two groups of SP140 high and SP140 low based on the median of SP140 expression. The protein levels of LCK, CASP7, CDKN1B, and PXN were compared between the two groups by Student’s t-test, and the p value was calculated after Benjamini-Hochberg correction. (E) Disease-specific survival of patients with high levels of SP140 (n=261) and low levels of SP140 (n=261) in TCGA HNSCC. The p value was calculated based on the log-rank test. **P<0.01, ***P<0.001 after correction for multiple comparisons. HNSCC, head and neck squamous cell carcinoma; RPPA, reverse phase protein array; SP140, speckled protein 140; TCGA, The Cancer Genome Atlas.