TABLE 2.
IL-5 and IFN-γ responses from PBMCs stimulated with S. mansoni vaccine candidate antigens for subjects from an area where schistosomiasis is endemic
| Antigen | Cytokine | No. of patients | % Respondersa | Cytokine level (pg/ml)
|
|
|---|---|---|---|---|---|
| Range | Mean ± SEM | ||||
| Paramyosin | IL-5 | 116 | 53 | 0–9,713 | 1,013 ± 170 |
| IFN-γ | 119 | 50 | 0–1,937 | 126 ± 25 | |
| IrV-5 | IL-5 | 116 | 29 | 0–2,388 | 57 ± 82 |
| IFN-γ | 119 | 61 | 0–9,027 | 284 ± 83 | |
| MAP-3 | IL-5 | 111 | 26 | 0–399 | 37 ± 8 |
| IFN-γ | 115 | 3 | 0–516 | 11 ± 5 | |
| MAP-4 | IL-5 | 116 | 40 | 0–2,208 | 67 ± 20 |
| IFN-γ | 118 | 14 | 0–629 | 24 ± 8 | |
Responder level, ≥30 pg/ml.