Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Dec 14;24:273. doi: 10.1186/s13075-022-02964-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 4 — Satb2 plays a role in osteogenic differentiation of BMSCs. A NGS was applied for mRNA expression detection in BMSCs after osteogenic induction for 0 (NC) and 3 (T) weeks. B RT-qPCR results showing abnormal mRNA expression. Data are denoted as the mean ± SD. ^**P < 0.01, ^***P < 0.001 vs. NC. C RT-qPCR detection giving Satb2 expression during BMSC osteogenic differentiation. Data are denoted as the mean ± SD. ^**P < 0.01, ^***P < 0.001 vs. 0 day. D RT-qPCR detection giving Satb2 expression in BMSCs after siRNA transfection against Satb2 (si-Satb2) or negative control (NC). Data are expressed as the mean ± SD. E, F RT-qPCR data giving RUXN2 and OCN expression after osteogenic induction for 3 weeks. Outputs are expressed as the mean ± SD. G Immunohistochemical staining for ALP and alizarin red staining showing BMSC osteogenic differentiation ability post silencing Satb2. ^***P < 0.001 vs. NC