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. 2022 Dec 14;41:344. doi: 10.1186/s13046-022-02552-6

Table 3.

Concurrent therapy and prognostic factors

MGMT
(methylated, not methylated)
IDH
(mutated, not mutated)
Age (years)
(59 or less, > 60)
KPS
(90 or 100, 70 or 80)
No vaccine (n = 3) 1 vs 2 0 vs 3 1 vs 2 2 vs 1
2 or 3 vaccinations, no concurrent therapy (n = 8) 3 vs 5 1 vs 7 4 vs 4 1 vs 7
Concurrent TMZ alone (n = 29) 8 vs 21 4 vs 25 18 vs 11 17 vs 12
Concurrent TMZ + bevacizumab (n = 11) 3 vs 8 2 vs 9 7 vs 4 6 vs 5
Concurrent TMZ + TTF (n = 6) 3 vs 3 0 vs 6 2 vs 4 3 vs 3
Concurrent TMZ + TTF + bevacizumab (n = 3) 1 vs 2 0 vs 3 1 vs 2 2 vs 1
Total (n = 60) 19 vs 41 7 vs 53 33 vs 27 31 vs 29

IDH isocytrate dehydrogenase, MGMT O-6-methylguanine-DNA methyltransferase, TMZ temozolomide, TTF tumor treating fields;