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. 2022 Dec 14;20:596. doi: 10.1186/s12967-022-03803-y

Table 2.

Differences in longitudinal quality of life (QoL) assessed by SF36 and FACT-BMT Form between HID and MSD patients

QoL HSCT (HID vs. MSD) Time (months post-HSCT)
β (95% CI) a P β (95% CI) a P
SF-36
 GH 5.46 (0.62, 10.29) 0.027b 0.03 (− 0.15, 0.22) 0.722
 PF 2.83 (− 3.15, 8.82) 0.353 0.30 (0.07, 0.52) 0.011b
 RP 4.06 (− 1.83, 9.94) 0.177 0.82 (0.44, 1.20)  < 0.001b
 RE 4.83 (− 4.41, 14.08) 0.306 0.33 (-0.10, 0.76) 0.129
 SF 4.21 (− 2.08, 10.51) 0.190 0.68 (0.41, 0.94)  < 0.001b
 BP 4.06 (− 0.79, 8.91) 0.101 0.09 (− 0.09, 0.27) 0.336
 VT 6.18 (1.37, 11.00) 0.012b 0.12 (− 0.05, 0.29) 0.168
 MH 4.53 (0.38, 8.68) 0.032b − 0.07 (− 0.20, 0.08) 0.333
FACT-BMT
 PWB 1.49 (0.11, 2.87) 0.034b 0.09 (0.04, 0.14)  < 0.001b
 SWB 1.29 (0.21, 2.38) 0.020b − 0.05 (− 0.10, 0.01) 0.099
 EWB 0.47 (− 0.57, 1.50) 0.378 − 0.01 (− 0.04, 0.02) 0.482
 FWB 1.89 (0.52, 3.26) 0.007b 0.02 (− 0.06, 0.10) 0.560
 FACT-G 5.34 (1.72, 8.76) 0.004b 0.05 (− 0.11, 0.20) 0.545
 TOI 2.80 (0.43, 5.18) 0.021b 0.09 (− 0.01, 0.19) 0.095
 FACT-BMT 4.64 (1.09, 8.19) 0.010b 0.03 (− 0.12, 0.17) 0.727

GH general health, PF physical functioning, RP role physical, RE role emotional, SF social functioning, BP bodily pain, VT vitality, MH mental health, PWB physical well-being, FWB functional well-being, SWB social well-being, EWB emotional well-being, FACT-BMT total with BMT module, TOI, FACT-BMT Trial Outcome Index (TOI)

aModel adjusted for age, sex, education, body mass index (BMI), main caregivers, diagnosis, transplantation type, history of aGVHD and cGVHD, and history of infection

bIndicates the statistical significance for the factors