Table 4.
The results of the univariate and multivariate Cox regression analysis
| Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| Age | < 0.001 | < 0.001 | ||
| <60 | Ref | Ref | ||
| ≥ 60 | 3.508(1.904–6.464) | 3.146(1.699–5.826) | ||
| Year of diagnosis | 0.008 | 0.054 | ||
| 1992–2002 | Ref | |||
| 2003–2012 | 0.524(0.333–0.826) | |||
| 2013–2018 | 0.473(0.251–0.89) | |||
| Sex | 0.758 | |||
| Male | ||||
| Female | ||||
| Race | 0.189 | |||
| White | ||||
| Others | ||||
| Laterality | 0.051 | 0.115 | ||
| Unilateral | ||||
| Bilateral | ||||
| Unknown | ||||
| Primary site | 0.004 | 0.15 | ||
| Retina | Ref | |||
| Choroid | 0.156(0.047–0.52) | |||
| Ciliary body | 0.286(0.124–0.662) | |||
| Vitreous | 0.288(0.137–0.606) | |||
| Pathological type | < 0.001 | 0.008 | ||
| DLBCL | Ref | Ref | ||
| MALT | 0.144(0.065–0.322) | 0.233(0.101–0.534) | ||
| NHL, NOS | 0.587(0.325–1.062) | 0.823(0.439–1.543) | ||
| Other/unclassifiedb | 0.59(0.361–0.964) | 0.813(0.489–1.353) | ||
| Ann arbor stage | 0.057 | |||
| I to II | ||||
| III to IV | ||||
| Unknown | ||||
| Surgery | 0.441 | |||
| NO | ||||
| Performed | ||||
| Radiotherapy | 0.362 | |||
| No/unknown | ||||
| Performed | ||||
| Chemotherapy | < 0.001 | 0.003 | ||
| No/unknown | Ref | Ref | ||
| Performed | 0.415(0.273–0.632) | 0.498(0.316–0.785) | ||