Table 3.
Predictive Factors of Complete Response to Treatment in Patients with iHES
| Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
| OR | CI | P | OR | CI | P | |
| Female | 1.882 | 0.473–7.488 | 0.369 | 256.096 | 0.755–86,870.318 | 0.062 |
| Age at diagnosis, year | 1.011 | 0.976–1.046 | 0.541 | 1.085 | 0.939–1.254 | 0.270 |
| Time interval between symptom onset and diagnosis, months | 0.985 | 0.955–1.016 | 0.337 | 0.970 | 0.919–1.024 | 0.273 |
| Asthma | 0.773 | 0.138–4.319 | 0.769 | 11.335 | 0.011–11,211.417 | 0.490 |
| Allergic rhinitis | 0.348 | 0.057–2.132 | 0.254 | 0.060 | 0.000–56.090 | 0.421 |
| Atopy | 0.563 | 0.170–1.864 | 0.347 | 0.198 | 0.011–3.554 | 0.272 |
| Presence of clinical manifestation at initial presentation | 0.444 | 0.113–1.743 | 0.245 | 0.969 | 0.033–28.829 | 0.985 |
| Number of involved organs | 1.861 | 1.016–3.409 | 0.044 | 4.395 | 1.033–18.699 | 0.045 |
| Whole blood count_initial, × 109 /L | 1.000 | 1.000–1.000 | 0.900 | 1.000 | 1.000–1.000 | 0.584 |
| Eosinophil count_initial, × 109 /L | 1.000 | 1.000–1.000 | 0.876 | 1.000 | 1.000–1.000 | 0.948 |
| Hemoglobin_initial, g/dL | 0.901 | 0.648–1.253 | 0.535 | 3.387 | 0.745–15.399 | 0.114 |
| Platelet_initial, × 109 /L | 0.993 | 0.987–0.999 | 0.034 | 0.983 | 0.964–1.002 | 0.074 |
| Total IgE, IU/mL | 1.000 | 0.999–1.000 | 0.086 | 0.999 | 0.998–1.000 | 0.051 |
| Maximal daily dose of corticosteroids | 1.011 | 0.994–1.029 | 0.212 | 1.036 | 0.970–1.107 | 0.295 |
Abbreviations: iHES, idiopathic hypereosinophilic syndrome; OR, odds ratio; CI, confidence interval; IgE, immunoglobulin E.