Table 1.
Comparison of Outcome Variables Between the Malassezia Folliculitis Positive Group and Malassezia Folliculitis Negative Group in Patients Clinically Diagnosed with Acne Vulgaris (n =320)
| Variables | MF Positive (n=92) | MF Negative (n=228) | p-value* |
|---|---|---|---|
| Age, mean (SD), years | 23.0(7.7) | 26.6(7.5) | 0.001 |
| Age < 20 years, n (%) | 42(45.6) | 52(22.8) | <0.001 |
| Male sex, n (%) | 32(34.8) | 50(21.9) | 0.017 |
| Itchy symptom, n (%) | 33(35.9) | 13(5.7) | <0.001 |
| Dandruff, n (%) | 29(31.5) | 15(6.6) | <0.001 |
| Underlying seborrheic dermatitis, n (%) | 7(7.6) | 10(4.4) | 0.245 |
| Disease severity of acne, n (%) | |||
| Grade 1, mild | 39(42.4) | 74(32.5) | 0.209 |
| Grade 2, moderate | 46(50.0) | 138(60.5) | |
| Grade 3, severe | 7(7.6) | 16(7.0) | |
| Location of acne, n (%) | |||
| Forehead | 77(83.7) | 102(44.7) | <0.001 |
| Scalp and hairline | 55(59.8) | 19(8.3) | <0.001 |
| Cheek | 71(71.2) | 183(80.3) | 0.536 |
| Chin | 50(54.3) | 144(63.2) | 0.144 |
| Neck | 15(16.3) | 13(5.7) | 0.002 |
| Upper chest | 23(25.0) | 6(2.6) | <0.001 |
| Upper back | 57(62.0) | 17(7.5) | <0.001 |
| Prior medication used, n (%) | |||
| Oral or topical steroid use | 10(10.8) | 10(4.4) | 0.002 |
| Oral antibiotics | 4(4.4) | 11(4.8) | 0.855 |
| Topical clindamycin | 36(39.1) | 127(55.7) | 0.007 |
| Topical benzoyl peroxide | 23(25.0) | 91(39.9) | 0.012 |
| Topical retinoid | 2(2.2) | 12(5.3) | 0.221 |
Notes: *Chi-square or Fisher’s exact test (categorical data) and independent t-test (numeric data) were used to compare the MF positive and MF negative groups.
Abbreviation: MF, Malassezia folliculitis.