FIG. 3.
Effect of anti-CD40L (αCD40L) treatment on IL-10KO mice infected with T. gondii. (A) IL-10KO mice infected with T. gondii were treated with 200 μg of anti-CD40L (n = 11) or isotype control hamster IgG (n = 11) at days 6 and 8 postinfection, and survival was monitored (P ≥ 0.05). (B) Serum levels of IFN-γ and IL-12 p40 at day 8 postinfection from infected IL-10KO mice treated with anti-CD40L (n = 11) or hamster IgG (n = 10) at days 6 and 8 postinfection. Results shown are pooled data from three separate experiments ± standard deviation.