Table 3.

Schematic overview of the mean dose intensity and frequency of ≥grade 3 toxicity in the four different patient groups.

	Normal DPD activity	Low DPD activity
DPYD variant	N = 16	N = 6	N = 22
	Mean dose intensity 78%	Mean dose intensity 67%
	Severe toxicity 25%	Severe toxicity 50%
DPYD non-variant	N = 182	N = 24	N = 206
	Mean dose intensity 91%	Mean dose intensity 84%
	Severe toxicity 29%	Severe toxicity 21%
	N = 198	N = 30	N = 228
Total