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. 2021 Dec 7;51(6):1785–1799. doi: 10.1093/ije/dyab248

Table 5.

Risk of neonatal and post-neonatal infant mortality and of child stunting and wasting at 18 months of age according to gestational age and weight at birth categoriesa

Birth outcome Neonatal mortality
Post-neonatal infant mortality
Child stunting at 18 months
Child wasting at 18 months
n/N (95% CI) RR (95% CI) n/N (95% CI) HR (95% CI) n/N % (95% CI) RR (95% CI) n/N % (95% CI) RR (95% CI)
Term 37/3001 12.3 (9.0, 17.0) 1.0 30/2964 10.0 (7.2, 14.1) 1.0 837/2878 29.1 (27.4, 30.8) 1.0 81/2865 2.8 (2.3, 3.5) 1.0
Preterm 50/666 75.1 (57.6, 97.2) 6.1 (4.0, 9.2) 13/616 22.7 (13.4, 38.4) 2.1 (1.1, 4.1) 261/583 44.8 (40.8, 48.8) 1.5 (1.4, 1.7) 17/578 2.9 (1.9, 4.6) 1.0 (0.6, 1.7)
≥2500 g 44/3333 13.2 (9.9, 17.5) 1.0 34/3289 10.6 (7.6, 14.8) 1.0 938/3183 29.4 (27.9, 31.1) 1.0 83/3165 2.6 (2.1, 3.2) 1.0
<2500 g 43/334 128.7 (96.7, 169.4) 9.8 (6.5, 14.6) 9/291 30.9 (16.0, 58.8) 3.3 (1.6, 7.0) 160/278 57.6 (51.6, 63.3) 2.0 (1.7, 2.2) 15/278 5.4 (3.3, 8.7) 2.1 (1.2, 3.5)
AGA 71/3076 23.1 (18.3, 29.1) 1.0 34/3005 11.6 (8.4, 16.1) 1.0 831/2908 28.6 (26.9, 30.3) 1.0 69/2892 2.4 (1.9, 3.0) 1.0
SGA 16/591 27.1 (16.7, 43.5) 1.2 (0.7, 2.0) 9/575 15.6 (8.3, 29.4) 1.5 (0.7, 3.2) 267/553 48.3 (44.2, 52.3) 1.7 (1.5, 1.9) 29/551 5.3 (3.7, 7.4) 2.2 (1.4, 3.4)
Term NBW 31/2851 10.9 (7.7, 15.3) 1.0 26/2820 9.2 (6.2, 13.8) 1.0 763/2739 27.9 (26.1, 29.6) 1.0 73/2726 2.7 (2.1, 3.4) 1.0
Preterm NBW 13/482 27.0 (16.0, 45.1) 2.5 (1.3, 4.7) 9/469 19.2 (9.9, 36.8) 1.8 (0.8, 4.1) 175/444 39.4 (35.0, 44.0) 1.4 (1.2, 1.6) 10/439 2.3 (1.2, 4.2) 0.9 (0.4, 1.6)
Term LBW 6/150 40.0 (18.1, 86.2) 3.7 (1.6, 8.7) 4/144 27.8 (10.6, 70.8) 3.3 (1.1, 9.5) 74/139 53.2 (44.9, 61.4) 1.9 (1.6, 2.2) 8/139 5.8 (2.9, 11.1) 2.1 (1.1, 4.4)
Preterm LBW 37/184 201.1 (148.2, 266.9) 18.5 (11.8, 29.1) 5/147 34.0 (14.6, 77.3) 4.1 (1.5, 10.7) 86/139 61.9 (53.9, 69.3) 2.2 (1.9, 2.6) 7/139 5.0 (2.4, 10.2) 1.9 (0.9, 4.0)
Term LBW 6/150 40.0 (18.1, 86.2) 1.0 4/144 27.8 (10.6, 70.8) 1.0 74/139 53.2 (44.9, 61.4) 1.0 8/139 5.8 (2.9, 11.1) 1.0
Preterm LBW 37/184 201.1 (148.2, 266.9) 5.0 (2.2, 11.6) 5/147 34.0 (14.6, 77.3) 1.2 (0.3, 4.6) 86/139 61.9 (53.9, 69.3) 1.2 (0.9, 1.4) 7/139 5.0 (2.4, 10.2) 0.9 (0.3, 2.3)
Preterm NBW 13/482 27.0 (16.0, 45.1) 1.0 9/469 19.2 (9.9, 36.8) 1.0 175/444 39.4 (35.0, 44.0) 1.0 10/439 2.3 (1.2, 4.2) 1.0
Preterm LBW 37/184 201.1 (148.2, 266.9) 7.5 (4.1, 13.7) 5/147 34.0 (14.6, 77.3) 2.3 (0.7, 7.2) 86/139 61.9 (53.9, 69.3) 1.6 (1.3, 1.9) 7/139 5.0 (2.4, 10.2) 2.2 (0.9, 5.7)
AGA Term 26/2453 10.6 (7.1, 15.7) 1.0 21/2427 8.7 (5.6, 13.4) 1.0 595/2363 25.2 (23.5, 27.0) 1.0 56/2352 2.4 (1.8, 3.1) 1.0
SGA Term 11/548 20.1 (11.3, 35.4) 1.9 (0.9, 3.8) 9/537 16.8 (8.6, 32.5) 2.1 (1.0, 4.7) 242/515 47.0 (42.6, 51.4) 1.9 (1.7, 2.1) 25/513 4.9 (3.3, 7.1) 2.0 (1.3, 3.2)
AGA Preterm 45/623 72.2 (54.6, 94.9) 6.8 (4.2, 11.0) 14/578 24.2 (14.4, 40.4) 2.7 (1.3, 5.5) 236/545 43.3 (39.1, 47.5) 1.7 (1.5, 1.9) 13/540 2.4 (1.4, 4.1) 1.0 (0.6, 1.8)
SGA Preterm 5/43 116.3 (48.9, 251.2) 11.0 (4.4, 27.2) 0/38 25/38 65.8 (49.7, 78.9) 2.6 (2.1, 3.3) 4/38 10.5 (4.2, 23.9) 4.4 (1.7, 11.6)
a

RR, risk ratio; HR, hazard ratio; SGA, small for gestational age defined as <10th centile weight for gestational age using Intergrowth Fetal Growth Standards; AGA, appropriate for gestational age; LBW, low birthweight defined as weight <2500 g at birth; NBW, normal birthweight.